Mesotherapy Serums

Best Mesotherapy Serums For Microneedling

Enhances microneedling face treatments to nourish, hydrate, and place nutrients in the skin to naturally reduce fine lines and wrinkles by improving skin cell strength.

Mesotherapy Serum based microneedling treatments have become increasingly popular among clients who wish to achieve skin rejuvenation via wound healing and collagen induction therapy.

Mesotherapy Serums For Face

One of the most effective non-invasive skin treatments is microneedling with mesotherapy serums because it works wonders for ageing skin issues, like saggy skin, wrinkles, age spots, and acne scars. The effectiveness of microneedling treatments depends largely on the type of serum used.


Active Nutritious Ingredients
Boost Fibroblast Activity
Stimulates Collagen Production
Increase Skin Cell Strength
Improve Skin Health
Restores Radiance and Glow

Benefits of Mesotherapy Serum

Mesotherapy serums create an optimal environment for the creation of fibroblast activity to produce collagen, elastin, and hyaluronic acid.

But not all mesotherapy serums for micro-needling are the same as the ingredients within the serums will vary. The meso-serum used in my Skin Clinic has been formulated by Fillmed and is called NCTF® 135HA

Mesotherapy Serum from Fillmed is a unique formula of 59 active ingredients. Created by a French Doctor in 1978, it remains unchallenged by recent competitors in positive pro-aging and improving skin health.

mesotherapy serums

How Does Mesotherapy Serum Work?

The poly-revitalising solution provides your dermis with essential ingredients to regenerate and improve cell membrane strength. The New Cellular Treatment Factor (NCTF®) smoothes out fine lines, restores radiance, deeply nourishes the skin, and increases the density of the dermis.

Meaning New Cellular Treatment Factor [NCTF] the lightweight active molecules stimulate cell communication within your skin layer without creating the 'Filler' look. (No facial features or expressions will be frozen or filled) It’s a particularly effective solution for recreating the ideal conditions for regeneration of the skin not freezing it in time

Instead, the serum floods the skin cells and rests between the cells to encourage the absorption of the nutrients, peptides, and growth factors. The strength of your skin cells becomes enhanced instantly, this results in visibly hydrated, clear, smooth, and toned skin.

The mesotherapy serum has been created for aesthetics medical practitioners hence has a CE Mark to confirm its efficacy in micro-skin needling and mesotherapy skin treatments. 

It's essential to note that not all serums are the same nor are they as active when placed into the dermis like NCTF135HA serum. 

Mesotherapy with Serum

Individual Cost £375

For all skin concerns, for example, fine lines, wrinkles, open pores, and blemishes. Stimulates collagen and is the best skin treatment for all skin rejuvenation needs. 

Read More

Mesotherapy with PRP

Individual Cost £495

Thin skin that needs tightening, for example, crepey neck, creases on décolletage, crows feet and eyebrow lift.

Read More

Skin Rejuvenation Plan

Four Treatments £1295

Effectively and drastically improve the appearance of hollow eyes and dark circles, as well as reduce nasolabial folds, marionette lines, peri-oral lines and skin of the neck, chest and hands. 

Read More

Skin Rejuvenation is used to describe the action of natural aesthetics skin treatments and this is the outcome when using a mesotherapy serum [NCTF 135HA] with skin micro needling treatments to correct the effects of ageing skin.

Mesotherapy serums

Mesotherapy Serums vs. Skincare Serums

Microneedling is an advanced skin aesthetics procedure using tiny needles penetrating the skin surface to encourage the production of collagen and toning of the tissues. Also known as Collagen Induction Therapy (CIT) 

Used in conjunction with a mesotherapy serum, which also acts as a buffer between the needles and the skin itself. As explained by the International Journal of Dermatology, the active solution of mesotherapy serums can be injected directly into the affected area, so they are excellent for those who want to tackle dehydrated, dull, puffy, or saggy skin.   

Mesotherapy serums are crucial for a successful micro needling treatment because they place the ingredients to nourish, hydrate, and feed the skin cells as the needles penetrate the dermis. 

When the skin cells in the dermis are traumatized by the injection of the needles, the exact nutrient support is placed in the perfect environment for the skin cells to absorb and regenerate with everything they need to be stronger and nourished.  

Mesotherapy serums have a smaller and light molecular weight than normal skincare serums. This enables the undeveloped skin cells in the dermis to recognize the essential active ingredients required for its growth and strength as it matures.

Your normal everyday serums are unable to be that active or at the right molecular level as they need to sit on the shelf in the warehouse for a few months. This is why you will see all mesotherapy serums in a single-use, air-tight glass bottle.

Now that you know the relationship between microneedling serums, let’s get into the differences between mesotherapy serums and normal serums:

Mesotherapy serums are medical-grade fluids designed to be injected into the skin, while normal serums are formulated to be applied to the skin’s surface.
Mesotherapy serums contain fewer chemical compounds than normal serums, because they created to target very specific skin cell communications
Most meso-serums contain specific mixtures of enzymes, plant extracts, and vitamins to help tackle skin health during the developing phase, while normal serums will include a wider variety of ingredients to communicate to mature skin cells.

For this reason, it is crucial to choose mesotherapy serums when needling into your skin, as your on skin serums won’t be able to influence the younger skin cell health and can cause a reaction as designed to be placed in the skin, but more importantly, won't add any value to your skin health. Save your target serum for everyday skin care routine not during a skin needling treatment.

Benefits of Mesotherapy Serums

Mesotherapy serums have had a big impact on the way modern advanced aesthetic skin treatments are changing. Whether the skin is sun-damaged, aging, or pigmented, the right serum will successfully regenerate the affected cells. For this reason, it is crucial to choose products that will favor the skin’s health in the short and long term. 

In my Clinic FILLMED NCTF 135HA, is the only mesotherapy used in treatments. As one of the best solutions for ageing skin issues such as hydration, open pores, black heads, fine lines, wrinkles, pigmentation, blemishes and saggy skin.

Now you know a ton of helpful information about microneedling treatments and mesotherapy serums, most notably how they work and what they can do for your skin.

Jen Adams

Subscribe and click the bell to be notified when I share my open and honest advice on improving your skin health to slow down the effects of ageing on the Health Hub on YouTube.


6a Park Street
Leamington Spa
CV32 4QN


Tuesday: 9 am to 6 pm
Wednesday: 12 noon to 6 pm
Thursday: 9 am to 6 pm
Friday: 12 noon to 6 pm
Saturday: 9 am to 6 pm

Strictly by Appointment